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College of Biological Science and Engineering

王国增

发布日期:2019-12-08 发布者:宝博网页版登录界面

 

姓名:王国增

性别:男

职称:副研究员

学历:博士

电话:

电子邮件:wanggz@fzu.edu.cn

宝博网页版登录界面:研究方向:1.极端酶功能及应用;2.合成生物学;3.酶工程

教育工作经历:

2002-2006:东北农业大学,学士

2006-2011:中国农业科学院研究生院,博士

2011-2013:中国农业科学院生物技术研究所,助理研究员

2017-2018:德国汉堡大学,访问学者

2013-今:宝博网页版登录界面,副研究员

教学简介:

本科生课程:蛋白质与酶工程,基因工程

研究生课程:现代微生物生物技术,应用蛋白质化学

科研简介:

在极端环境微生物酶发掘、酶的结构功能、合成生物学等领域进行了深入研究。主持国家自然基金青年基金项目1项,福建省高校杰出青年人才项目1项,福建省自然科学基金项目、校人才基金和校科技发展基金等共4项,作为课题骨干参加国家863项目1项。在Bioresource Technology、Scientific Reports、PLoS ONE、Applied   Microbiology and Biotechnology、Biochemical   and Biophysical Research Communications等刊物上发表SCI论文25篇,其中以第一作者或通讯作者发表17篇。申请发明专利6, 其中获得授权4项。

社会兼职:

福建省微生物学会理事

科研项目:

1. 福建省自然科学基金,2019J01237,瘤胃微生物木聚糖酶基因在食物消化周期中的表达规律及功能特性研究,2019.06-2022.05,主持。

2. 福建省高校杰出青年科研人才计划,SW2015-01,宏基因组技术发掘和利用盐碱湖中极端微生物碱性酶基因资源,2015.07-2017.12,主持。

3. 福建省自然科学基金,2015J05066,大布苏盐碱湖底泥微生物宏基因组中新木聚糖酶基因克隆表达及其特性研究,2015.04-2018.03,主持。

4. 国家自然科学基金青年基金项目,31301406,山羊瘤胃微生物宏基因组来源的低温木聚糖酶XynGR40冷适应机制的研究,2014.01-2016.12,主持。

5、校人才基金,XRC-1326,盐碱湖微生物木聚糖酶基因多样性及新基因克隆和酶特性研究,2013.06-2015.08,主持。

6、校科技发展基金,2013-XY-16,北极海洋底泥微生物新木聚糖酶基因克隆及酶学特性研究, 校科技发展基金, 2013.07-2015.12,主持

7、国家高技术研究发展计划,2012AA022105,基因组多位点快速进化与改良,2012.12-2015.12,参与。

专利

(1)一种碱性耐盐普鲁兰酶PulA及其基因和应用,2017, 专利号: ZL201710584710.7

(2)一种木聚糖酶XynMF10及其基因和应用,2017, 专利号: ZL 201710584732.3

(3) 一种耐盐耐有机溶剂的低温碱性酯酶EstSL3及其基因和应用,2015, 专利号:ZL201510668911.6

(4) 一种低温木聚糖酶XYNGR40及其基因和应用,2010,专利号:ZL201010238563.6

(5) 一种高温碱性耐盐木聚糖酶XynSL4及其基因和应用,2014, 申请号:   CN201410629920.X

(6)一种极端嗜盐、耐表面活性剂的非钙离子依赖型α-淀粉酶及其基因和应用,2019, 申请号: CN109628429A

以第一作者或通讯作者发表的论文:(*为通讯作者)

[1] Ren Y, Luo H, Huang H, Hakulinen N, Wang Y,   Wang Y, Su X, Bai Y, Zhang J, Yao B, Wang G*, Tu T*, Improving the   catalytic performance of Proteinase K from Parengyodontium album for   use in feather degradation, International Journal of Biological   Macromolecules 154 (2020) 1586-1595

[2] Xiao Q, Han J,   Jiang C, Luo M, Zhang Q, He Z, Hu J*, Wang G*, Novel Fusion Protein   Consisting of Metallothionein, Cellulose Binding Module, and Superfolder GFP   for Lead Removal from the Water Decoction of Traditional Chinese Medicine.   ACS Omega, 5 (2020) 2893-2898

[3] G. Wang*, Y.   Ren, T.B. Ng, W.R. Streit, X. Ye, High-throughput amplicon sequencing   demonstrates extensive diversity of xylanase genes in the sediment of soda   lake Dabusu, Biotechnology Letters 41(3) (2019) 409-418

[4] G.   Wang*, M. Luo, J. Lin, Y. Lin, R. Yan, W.R. Streit, X. Ye A new extremely   halophilic, calcium-independent and surfactant- resistant alpha-amylase from Alkalibacterium sp. SL3, Journal of   Microbiology and Biotechnology 29 (2019) 765-775.

[5] J. Wu, R. C. Qiu, Y. Ren, Yan, X. Ye, G. Wang*, Novel salt-tolerant   xylanase from a mangrove-isolated fungus Phoma   sp. mf13 and its application in Chinese steamed bread, ACS Omega 3 (2018)   3708-3716.

[6] G.   Wang, J. Wu, R. Yan, J. Lin*, X. Ye*, A Novel Multi-domain High   Molecular, Salt-Stable Alkaline Xylanase from Alkalibacterium sp. SL3, Frontiers in Microbiology 7 (2017) 2120.

[7] G.   Wang, J. Wu, J. Lin, X. Ye*, B. Yao*, The disruption of two salt bridges   of the cold-active xylanase XynGR40 results in an increase in activity, but a   decrease in thermostability, Biochemical and Biophysical Research Communications   481(1-2) (2016) 139-145.

[8] G.   Wang, Q. Wang, X. Lin, T.B. Ng, R. Yan, J. Lin*, X. Ye*, A novel   cold-adapted and highly salt-tolerant esterase from Alkalibacterium sp. SL3 from the sediment of a soda lake,   Scientific Reports 6 (2016) 19494.

[9] X. Huang, J. Lin, X. Ye, G. Wang*, Molecular characterization of a thermophilic and salt-   and alkaline-tolerant xylanase from Planococcus   sp. sl4, a strain isolated from the sediment of a soda lake, Journal of Microbiology   and Biotechnology 25(5) (2015) 662-671.

[10] G.   Wang, X. Huang, T.B. Ng, J. Lin*, X.Y. Ye*, High phylogenetic diversity   of glycosyl hydrolase family 10 and 11 xylanases in the sediment of Lake   Dabusu in China, PloS One 9(11) (2014) e112798.

[11] G.   Wang, K. Meng, H. Luo, Y. Wang, H. Huang, P. Shi, P. Yang, Z. Zhang*, B.   Yao*, Phylogenetic diversity and environment-specific distributions of   glycosyl hydrolase family 10 xylanases in geographically distant soils, PloS One   7(8) (2012) e43480.

[12] Y. Li#, G. Wang#, J. Tian, H. Liu, H. Yang, Y. Yi, J. Wang, X.   Shi, F. Jiang, B. Yao*, Z. Zhang*, Transcriptome analysis of the silkworm   (Bombyx mori) by high-throughput RNA sequencing, PloS One 7(8) (2012) e43713.

[13] G.   Wang, K. Meng, H. Luo, Y. Wang, H. Huang, P. Shi, X. Pan, P. Yang, B.   Yao*, Molecular cloning and characterization of a novel SGNH arylesterase   from the goat rumen contents, Applied Microbiology and Biotechnology 91(6)   (2011) 1561-1570.

[14] G.   Wang, H. Luo, Y. Wang, H. Huang, P. Shi, P. Yang, K. Meng, Y. Bai, B.   Yao*, A novel cold-active xylanase gene from the environmental DNA of goat   rumen contents direct cloning, expression and enzyme characterization,   Bioresource Technology 102(3) (2011) 3330-3336.

[15] G.   Wang, H. Luo, K. Meng, Y. Wang, H. Huang, P. Shi, X. Pan, P. Yang, Q.   Diao, H. Zhang, B. Yao*, High genetic diversity and different distributions   of glycosyl hydrolase family 10 and 11 xylanases in the goat rumen, PloS One   6(2) (2011) e16731.

[16] G.   Wang, Y. Wang, P. Yang, H. Luo, H. Huang, P. Shi, K. Meng, B. Yao*,   Molecular detection and diversity of xylanase genes in alpine tundra soil,   Applied Microbiology and Biotechnology 87(4) (2010) 1383-1393.

[17] H. Huang#, G. Wang#, Y. Zhao, P. Shi, H. Luo, B. Yao*, Direct and   efficient cloning of full-length genes from environmental DNA by RT-qPCR and   modified TAIL-PCR, Applied Microbiology and Biotechnology 87(3) (2010) 1141-1149.

获奖情况

中国农业科学院优秀博士论文(2012

福建省高校杰出青年人才(2015

指导研究生获得福建省优秀硕士论文(2017

 

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